What does the evidence actually say?

Every Wednesday, a clinical researcher weighs one viral health claim in plain language: what the research shows, how strong it is, and what's still unknown. The short answer is at the top, so it takes a minute. Free, with no sponsors.

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Who's writing this

I'm Justin Yamashita, MSc. I've worked three levels of clinical research: the bench, the site, and the CRO. Almost nobody outside the industry knows how a drug actually becomes a drug, from molecule to medicine, not because they aren't smart, but because nobody ever showed them. That gap is where fear gets sold.

None of this is abstract. Every medicine in your cabinet came through this system, and sooner or later you'll be deciding whether to start one, stop one, or trust something a stranger online swears by. For yourself, or for a parent.

Root to Rx is free and independent, with no sponsor. Also free: The Open Site File on Tuesdays, for people working in clinical research, and The Roots on Sundays, for the person who's the medical desk for their family. If it turns out to be useful, passing it to one person who needs it is how it grows.

  • Justin Yamashita, MSc., Global Clinical Trial Project Manager, and former clinical trial coordinator and lab rat playing with microbes, cell cultures, and microscopes.

Root to Rx

Justin Yamashita

Latest


What Is the Sunshine Act? What Drug Reps Can and Can't Do | Plain Talk, Issue 031

The Root Room

+3

What Is the Sunshine Act? What Drug Reps Can and Can't Do | Plain Talk, Issue 031

Justin Yamashita

•

Nov 11, 2026

Financial Disclosure Forms in Clinical Trials: What Coordinators Collect, and Why | The Open Site File #22

Financial Disclosure

+1

Financial Disclosure Forms in Clinical Trials: What Coordinators Collect, and Why | The Open Site File #22

Justin Yamashita

•

Nov 10, 2026

Why Do Prescriptions Cost So Much in the US? Who Actually Sets the Price | Plain Talk, Issue 030

The Root Room

+2

Why Do Prescriptions Cost So Much in the US? Who Actually Sets the Price | Plain Talk, Issue 030

Justin Yamashita

•

Nov 4, 2026

CRA, MSL or Drug Rep? Who's Who When Industry Visits a Research Site | The Open Site File #21

Sunshine Act

+1

CRA, MSL or Drug Rep? Who's Who When Industry Visits a Research Site | The Open Site File #21

Justin Yamashita

•

Nov 3, 2026

Are Generic Drugs as Good as Brand Name? Five Claims, Checked | Plain Talk, Issue 029

Generics

+2

Are Generic Drugs as Good as Brand Name? Five Claims, Checked | Plain Talk, Issue 029

Justin Yamashita

•

Oct 28, 2026

What to Do When a PI Asks You to Backdate a Consent | The Open Site File #20

Informed Consent

+1

What to Do When a PI Asks You to Backdate a Consent | The Open Site File #20

Justin Yamashita

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Oct 27, 2026

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